Research Project 3

Systems functional genomics of congenital heart disease

Project 3

Project 3 combines GWAS and omics analyses with hiPSC-cardiomyocyte validation to dissect the genetic basis of congenital heart disease, linking large-scale data to functional models of cardiac development.

Project Leader

Yiqiang Zhang, PhD

Project 3 Leader — Functional genomics of congenital heart disease

Mentors

Yuan Luo, PhD

External Mentor — Project 3

Internal mentor: Rachel Novotny, PhD

Research Staff & Trainees

Thong Ba Nguyen, PhD

Postdoctoral Bioinformatician · Postdoctoral Fellow, JABSOM

GWAS and omics analyses; hiPSC-cardiomyocyte validation experiments.
Graduate Research Assistant Position open

Computational genomics; congenital-heart-disease cellular assays; mouse-model validation.

Consultants & Collaborators

Andras Bratincsak, MD, PhD

Consultant — clinical cardiology · Professor of Pediatrics, JABSOM

Clinical cardiology guidance.
Robert Hufnagel, MD, PhD

Consultant — clinical genetics · Senior Investigator, Kaiser Permanente Hawaiʻi

Clinical genetics guidance.
Christopher Stefanelli, MD

Consultant — pediatric cardiology · Clinical Professor, JABSOM

Pediatric cardiology guidance.